Webinars (Archive)
C-Therm regularly offers online seminars - or "webinars" - to provide information on new applications and offer participants an opportunity to learn how C-Therm's clients are using the innovative sensor technology. The webinar is a combination of a downloadable support file, usually in the form of a powerpoint show, and a synchronoized audio recording. Please browse from the list of available archived webinar recordings below. For a list of upcoming LIVE webinars please visit here: Upcoming Webinars
Archived Webinar Recordings
Please browse our list of archived webinar recordings and register to receive access for any you feel would be beneficial.
Title: TCi's Application in the Thermal Conductivity Characterization of Explos ives
Description: Testing the thermal conductivity of most energetic materials is a challenge with more traditional techniques, as the required large volumes of material pose undesirable safety risks or the necessary sample geometries are impractical. This often leads to estimation of thermal conductivity in predictive models rather than actual measurement. The dependence of thermal conductivity of a material undergoing an exothermic reaction on local temperature has a significant effect on the critical conditions for thermal ignition.
The TCi Thermal Conductivity Analyzer's modified transient plane source technique (MTPS), developed in collaboration with the US Navy, offers the unique capability to measure the thermal conductivity of an energetic material directly as an alternative to the book values that are frequently substituted in the computational models. The TCi requires minimal volumes of material, utilizes extremely short testing time parameters (0.8 second) and employs a low energy measurement pulse that makes it the optimal solution in the characterization of energetics.
Recent published work will be reviewed in how the C-Therm TCi Thermal Conductivity Analyzer is used at the US Navy’s Naval Surface Warfare Center Indian Head (NAVSEA) Division and the Canadian Explosives Research Lab (CERL).
Title: TCi's Application in the Thermal Conductivity Characterization of Metal Hydrides
Launch Webinar
Download PDF of Slides
Description: The storage of hydrogen and the development of fuel cells are one of the main issues for the development of renewable energies in the next few years.
Metal hydrides specifically are receiving much attention as a storage media for hydrogen. In the development and characterization of metal hydrides for hydrogen absorption, the thermal conductivity of the material is a crucial material performance property. The thermal conductivity of the solid material is important to know how long it will take to get the pellets to an equilibrium temperature where they will begin releasing hydrogen. Furthermore, it is important to know the thermal conductivity of these pressed powders while engineering a storage device to use the powders commercially. The thermal conductivity of the material changes substantially from a powder to a compressed solid, necessitating the direct measurement of both material formats.
Results will be presented resulting from C-Therm’s collaboration with the University of New Brunswick’s Hydrogen Storage Materials group in applying the C-Therm TCi Thermal Conductivity Analyzer in the characterization of both powder and pellet formats within a glove box environment. Use of a glovebox is required in testing the materials due to the highly reactive state of the metal hydrides. The glovebox is purged with argon or nitrogen gas. The TCi’s unique ability to easily operate within the glovebox environment provides a significant advantage to researchers in the field of metal hydrides characterization. Learn more about the TCi’s application in metal hydride characterization.
Title: TCi's Application in the Thermal Conductivity Characterization of Nanomaterials
 Launch Webinar
Download PDF of Slides
Description: Nanomaterials are an exciting area of material science research and engineering. Nanomaterials offer unique electrical properties, extraordinary strength and great efficiency in heat conduction. Application areas for nanomaterials include electronics, optics, medicine and architecture - offering tremendous potential for groundbreaking discovery. The webinar will review application areas of the TCi Thermal Conductivity Analyzer in assisting with the development and characterization of nanomaterials.
In reviewing recent published work – we’ll look at how researchers at Texas Tech and Florida State Universities leverage the TCi’s capabilities to help investigate mechanical methods used to shorten carbon nanotubes (CNTs) for improving dispersion without reducing their thermal conductivity. Single walled carbon nanotubes (SWCNTs) were mechanically cut to produce short and open-ended fullerene pipes. These shortened SWCNTs were then used in polymer composites. Both atomic force microscopy and scanning electron microscopy characterizations suggested that nanotube shortening significantly improved CNT dispersion. Thermal conductivity of composites containing short CNTs were found to be much better than those containing pristine CNTs.
Similarly, researchers in the School of Materials and Mineral Resources Engineering at the Universiti Sains Malaysia employ the TCi Thermal Conductivity Analyzer for looking at the effects of surface-functionalized multi-walled carbon nanotubes (MWNTs) on the properties of poly(dimethyl siloxane) (PDMS). Learn more about the TCi’s application in nanomaterials characterization.
Title: Determining Granulation Endpoint with Effusivity
Guest Speaker: Dr. Rutesh Dave, Long Island University
Description: Wet granulation is one of the oldest methods to prepare granules and effectively monitoring the wet granulation process is important in the field of pharmaceuticals. To date significant has been made to determine endpoints of wet granulation using various techniques and still the problem exists. Scale-up issues due to batch to batch variation are the common causes of batch failure. The wet granulation of Avicel 101 (Microcrystalline Cellulose) was studied and from the data we were able to quantify the changes occurring during wet granulation and accurately determine the end point. This presentation will be useful for scientists involved in pre formulation, formulation and production.
Title: In-Line Monitoring Blend Operations Using Effusivity
%20Headshot.bmp) Guest Speaker: Stephen Closs
Manager of Pharmaceutics and Process Technology
Patheon Pharmaceutical Development Services Group
Description: Blending operations are integral to most solids pharmaceutical manufacturing today whether used to achieve a state of API and excipient uniformity as in a direct blend application or to provide optimal distribution of a functional excipient in an extra granular process stage such as final blend lubrication using magnesium stearate. Stephen Closs of Patheon will discuss the application of thermal effusivity as a PAT tool to optimize physical blend and lubrication operations.
Title: Thermal Conductivity Made Easy - Introduction to the TCi
 Speaker: Adam Harris, C-Therm
Description: Learn about the basics of operation to the C-Therm TCi Thermal Conductivity Analyzer. The TCi offers rapid, non-destructive thermal conductivity testing capability. Designed for lab, quality control and production environments, the TCi is factory calibrated and provides users broad testing ranges - from 0.035 to 100 W/mK at temperatures from (-50º C) to (200º C). The C-Therm TCi(tm) provides accurate thermal analysis of solids, liquids, powders and pastes in less time than any other instrument commercially available - in as little as 5 seconds! Samples require little to no preparation. They remain intact, undisturbed and reusable after testing. Discover how cost-effective it is to increase your thermal characterization capabilities - and how the C-Therm TCi can be equipped with dual sensors to accelerate your testing through-put. New application data will also be presented on correlation of thermal conductivity to milk fat content in highlighting one of the many applications of the TCi.
Title: Lubricant Systems Based on Ratios of Mg. St Polymorphs
 Guest Speaker: Patrick Okoye, Graduate Division of Pharmaceutical Sciences, Arnold & Marie Schwartz College of Pharmacy, Long Island University, Brooklyn, NY
Description: Magnesium Stearate is a common lubricant used in the Pharmaceutical industry, as it plays a significant role in the processablity of solid dosage formulations. Commercially available Magnesium stearate (MgSt) contains mixtures of the crystalline forms in unknown ratios. This presentation will investigate the use of effusivity in exploring the physicochemical characteristics of mixed lubricant systems comprising of known ratios of polymorphs of magnesium stearate (MgSt) in direct compressible formulations in an attempt to establish which form or combination of these polymorphs possesses the best lubricating properties, if any.
Title: Basics of Thermal Effusivity Application as a PAT Tool in the Pharmaceutical Industry
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Description: Learn about how the thermal property of effusivity (thermal inertia) can be leveraged in profiling various operations in processing of powders within the pharmaceutical industry. This presentation is offered as a basic introduction to the technology and will cover applications ranging from blend uniformity monitoring, lubrication, and end-point determination in fluid-bed drying.
Title: Thermal Conductivity Testing of Energetic Emulsions
  Guest Speaker(s): Shanti Singh (R) and Sandra Golthorp (L) from the Canadian Explosives Laboratory, Natural Resources Canada (NRC)
Description: June 2008 - This presentation is co-presented with users from the Canadian Explosives Laboratory (Natural Resources Canada). Learn about recent advancements to the C-Therm TCi Thermal Conductivity platform with the launch of the 2.0 platform and hear directly how users in the explosives field are leveraging this advanced thermal conductivity capability in the lab. This webinar would be of particular interest to any researchers in the field of energetics, explosives, and general emulsions. New features presented include: User-Cal Wizard and Blotter Technique for Testing through Layers.
Title: Statistical Experimental Design - the Keystone to QbD
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Guest Speaker: Andy Tallevi, Keller Consulting
Description: April 2008 - It’s a well-known fact that the pharmaceutical industry, sadly, lags behind many other industries when it comes to process control and automation. There are many examples of lower tech industries that have made huge strides in this area and are producing high quality products, very low rejects and close-to-zero process failures. FDA and other regulators have supported and encouraged the adoption of Quality by Design. There can be no doubt that pharmaceutical manufacturers must have this as their aim. At the core of Quality by Design is one supposition: process understanding. Without this it is not realistic to assume one can control, let alone automate, a process. One must understand what the critical factors that affect the process are, what the limits of failure for each factor are and what the feasible limits of control for each factor are. This talk will discuss how to achieve process understanding using statistical design. It will also discuss how the use of PAT tools such as effusivity will ensure Quality products are produced.
Title: Effusivity Profiling in Lubrication with Mg Stearate Mono- and Di- hydrate
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Guest Speaker: Dr. Stephen Wu, Covidien
Description: December 2007 - Listen in as Dr. Stephen Wu of Covidien (formerly Tyco Mallinckrodt) shares information on the effusivity profiling of Mono and Dihydrate Magnesium Stearate. Dr. Wu and Patrick Okoye (Mathis Instruments), published a paper that was featured in the September 2nd, 2007 issue of PharmTech, titled “Lubrication of Direct-Compressible Blends with Magnesium Stearate Monohydrate and Dihydrate”.
Title: Profiling of Commercial Batches Using Thermal Effusivity
 Guest Speaker: David Mayers, VP Quality, Purdue Pharma (Canada)
Launch Webinar
Description: Learn more about how effusivity was used in profiling commercial batches at Purdue Pharma (Canada). |
